Anti-CDK6 Polyclonal Antibody

品牌：solarbio | 货号：K002825P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002825P-50ul	solarbio	50ul	960.00元
K002825P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-CDK6 Polyclonal Antibody
别名	MCPH12;PLSTIRE
应用	WB IHC IF IP
稀释比例	WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-100.
交叉反应	Human Mouse Rat
蛋白分子量	37kDa
Gene ID	1021
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human CDK6
性状	液体
Public Immunogen Range	Recombinant protein of human CDK6
Subcellular Locations	Cell projection Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center ruffle
Swiss Prot	Q00534
克隆类型	Polyclonal Antibody
背景资料	The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.