IL7R monoclonal antibody, clone ANC8F2
产品名称： IL7R monoclonal antibody, clone ANC8F2
英文名称： IL7R monoclonal antibody, clone ANC8F2
产品编号： MAB6938
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant IL7R.
- Immunogen:
- Recombinant protein corresponding to human IL7R.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Comments on the article "Persistent confusion of total entropy and chemical system entropy in chemical thermodynamics" [(1996) Proc. Natl. Acad. Sci. USA 93, 7452-7453]
Ross J.Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14314; discussion 14315.
- 2.
- Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.
Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ.Science. 1993 Dec 17;262(5141):1877-80.
- 3.
- Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, et al..Cell. 1990 Mar 23;60(6):941-51.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 3575
- Gene Name:
- IL7R
- Gene Alias:
- CD127,CDW127,IL-7R-alpha,IL7RA,ILRA
- Gene Description:
- interleukin 7 receptor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq
- Other Designations:
- CD127 antigen,interleukin 7 receptor alpha chain
- Related Disease
- Arthritis, Juvenile Rheumatoid
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bronchial Hyperreactivity
- Carcinoma, Non-Small-Cell Lung
- Celiac Disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Helicobacter Infections
- HIV Infections
- Hyperparathyroidism, Secondary
- Kaposi Varicelliform Eruption
- Lung Diseases
- Lung Neoplasms
- Lymphoma, Large B-Cell, Diffuse
- Lymphomatoid Granulomatosis