Anti-HLA-DRA Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002368P-50ul	solarbio	50ul	960.00元
K002368P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-HLA-DRA Polyclonal Antibody
别名	HLA-DRA1
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Human Mouse
蛋白分子量	29kDa
Gene ID	3122
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human HLA-DRA
性状	液体
Public Immunogen Range	Recombinant protein of human HLA-DRA
Subcellular Locations	Cell membrane Endoplasmic reticulum membrane Endosome membrane Golgi apparatus Late endosome membrane Lysosome membrane Single-pass type I membrane protein trans-Golgi network membrane
Swiss Prot	P01903
克隆类型	Polyclonal Antibody
背景资料	HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.